Zhou Hui, Tan Chang-Heng, Jiang Shan-Hao, Zhu Da-Yuan
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, People's Republic of China.
J Nat Prod. 2003 Oct;66(10):1328-32. doi: 10.1021/np0301590.
Seven new and 15 known serratene-type triterpenoids were isolated from the whole plant of Huperzia serrata. The structures of these new triterpenoids were elucidated as 21alpha-hydroxyserrat-14-en-3beta-yl p-dihydrocoumarate (1), 21alpha-hydroxyserrat-14-en-3beta-yl dihydrocaffeate (2), 21alpha-hydroxyserrat-14-en-3beta-yl propanedioic acid monoester (3), 3alpha,21alpha-dihydroxyserrat-14-en-24-oic acid (4), 16-oxo-3alpha,21beta-dihydroxyserrat-14-en-24-al (5), 16-oxo-3alpha,21beta-dihydroxyserrat-14-en-24-oic acid (6), and 16-oxo-21beta-hydroxyserrat-14-en-3alpha-yl acetate (7), respectively, by means of spectroscopic analysis.
从蛇足石杉全草中分离得到7个新的和15个已知的锯齿烯型三萜类化合物。通过光谱分析，这些新三萜类化合物的结构分别被鉴定为21α-羟基锯齿-14-烯-3β-基对二氢香豆酸酯（1）、21α-羟基锯齿-14-烯-3β-基二氢咖啡酸酯（2）、21α-羟基锯齿-14-烯-3β-基丙二酸单酯（3）、3α,21α-二羟基锯齿-14-烯-24-酸（4）、16-氧代-3α,21β-二羟基锯齿-14-烯-24-醛（5）、16-氧代-3α,21β-二羟基锯齿-14-烯-24-酸（6）和16-氧代-21β-羟基锯齿-14-烯-3α-基乙酸酯（7）。
