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一种用于对竞争性立体定向放射外科治疗计划进行评分的简单可靠指标。

A simple and reliable index for scoring rival stereotactic radiosurgery plans.

作者信息

Wagner Thomas H, Bova Francis J, Friedman William A, Buatti John M, Bouchet Lionel G, Meeks Sanford L

机构信息

Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL 32224, USA.

出版信息

Int J Radiat Oncol Biol Phys. 2003 Nov 15;57(4):1141-9. doi: 10.1016/s0360-3016(03)01563-3.

Abstract

PURPOSE

A simple and robust index for ranking rival stereotactic radiosurgery plans is presented.

METHODS

The radiosurgery plan score index, CGI (Conformity/Gradient Index), is an average of a conformity score and a gradient score. Computation of the CGI score is simple, requiring only three pieces of data: (1) the total volume irradiated to the prescription isodose level, (2) the volume of the target, and (3) the total volume irradiated at half of the prescription isodose level. The overall CGI Index is a simple function of these three pieces of data.

RESULTS

When multiple sets of rival stereotactic radiosurgery plans were ranked with respect to this single score index, the resulting plan rankings closely matched the plan rankings according to biologic indices (calculated nontarget brain normal tissue complication probabilities).

CONCLUSIONS

The CGI is a simple and fast plan evaluation tool that can assist the radiosurgery planner in evaluating and optimizing multiple candidate radiosurgery plans.

摘要

目的

提出一种简单且稳健的用于对竞争性立体定向放射治疗计划进行排名的指标。

方法

放射治疗计划评分指标CGI(适形度/梯度指数)是适形度评分和梯度评分的平均值。CGI评分的计算很简单,只需要三个数据:(1)照射到处方等剂量水平的总体积,(2)靶区体积,(3)照射到处方等剂量水平一半时的总体积。总体CGI指数是这三个数据的简单函数。

结果

当根据这个单一评分指标对多组竞争性立体定向放射治疗计划进行排名时,所得计划排名与根据生物学指标(计算的非靶区脑正常组织并发症概率)得出的计划排名密切匹配。

结论

CGI是一种简单快速的计划评估工具,可协助放射治疗计划制定者评估和优化多个候选立体定向放射治疗计划。

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