Al-Khenaizan Sultan
Division of Dermatology, Department of Medicine, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
J Am Acad Dermatol. 2003 Nov;49(5 Suppl):S244-6. doi: 10.1016/s0190-9622(03)00123-3.
We describe a 4 1/2 -year-old Saudi Arabian boy born to consanguineous parents who was initially seen with gradual onset of fever and abdominal distention. The patient was found to have speckled hypopigmentation and hyperpigmentation of the sun-exposed areas. The finding of large cytoplasmic granules in blood and bone marrow leukocytes established the diagnosis of Chediak-Higashi syndrome. We review the literature on this finding, which might be underreported, especially in darkly pigmented races.
我们描述了一名4岁半的沙特阿拉伯男孩，其父母为近亲结婚。该男孩最初表现为逐渐出现发热和腹部膨隆。患者在暴露于阳光的部位出现斑点状色素减退和色素沉着。血液和骨髓白细胞中发现大的细胞质颗粒，从而确诊为切-希二氏综合征。我们回顾了关于这一发现的文献，该发现可能未得到充分报道，尤其是在肤色较深的种族中。
