Murthi G V S, Paterson L, Azmy A
Department of Surgical Paediatrics, Royal Hospital for Sick Children, Glasgow, Scotland, UK.
J Pediatr Surg. 2003 Oct;38(10):1543-5. doi: 10.1016/s0022-3468(03)00512-8.
Mesenchymal hamartoma of the liver is generally considered to be benign in nature, and surgical excision has been the treatment of choice. There have been 3 reports on the association of cytogenetic abnormalities with this tumor, and the possibility of malignant potential has been raised. The authors report a fourth case with a previously unreported complex chromosomal translocation between chromosomes 11, 17, and 19 at bands q12, p11, and q13.3, respectively in all cells examined and discuss the significance of this finding.
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