Oztürk Gülyüz, Bölükbaşi Selçuk, Unsal Tuğba, Songür Murat
Blood Center of Medicine Faculty of Gazi University, Beşevler, Ankara, Turkey.
Acta Orthop Traumatol Turc. 2003;37(4):313-8.
This retrospective study was performed to evaluate transfusions in orthopedic surgery and, in the light of our successful practice, to contribute to the development of appropriate transfusion policies in Turkey.
In this study 1,811 female patients who underwent orthopedic elective or emergency surgery from January 1997 to December 1999 (group 1) and from January 2000 to December 2002 (group 2) were retrospectively evaluated with respect to ordered and transfused blood units. Autologous blood transfusions were not included. Group 1 consisted of 990 patients (mean age 50.4 years); group 2 consisted of 821 patients (mean age 53.3 years). Maximum surgical blood order schedule (MSBOS) ratios and preference for red blood cell transfusions were determined. Perioperative target hemoglobin level was 10 gr /dL in both groups. In group 2, allogeneic blood transfusions were performed according to the principles established in January 2000, which aimed (i) to more precisely estimate blood loss during surgical procedures and to prevent inappropriate use of blood products; (ii) to reduce the frequency of "standard one unit transfusion" through administration of crystalloids and colloids to the extent of complete elimination of transfusions; and (iii) to use blood components (erythrocyte suspensions) instead of whole blood.
In both groups, the MSBOS ratios were below 2, being 1.83 in group 1, and 1.59 in group 2. The medians of requested and transfused blood units were 2 and 1 in group 1, and 3 and 2 in group 2, respectively, resulting in statistically significant differences (p<0.05). The "standard one unit transfusion" rate was 28.7% in group 1, and 18.9% in group 2. Preferences for red blood cell transfusions showed statistically significant increases over the consecutive years. The use of erythrocyte suspensions was found as 29.2% in group 1, and 95% in group 2.
Our data demonstrated that the transfusion policy established for orthopedic surgical procedures at our center resulted in successful applications thanks to a good cooperation between relevant departments and achieved the level of international standards.
本回顾性研究旨在评估骨科手术中的输血情况,并根据我们的成功实践,为土耳其制定合适的输血政策做出贡献。
本研究对1997年1月至1999年12月(第1组)以及2000年1月至2002年12月(第2组)期间接受骨科择期或急诊手术的1811例女性患者进行回顾性评估,评估内容包括所订购和输注的血制品单位。不包括自体输血。第1组包括990例患者(平均年龄50.4岁);第2组包括821例患者(平均年龄53.3岁)。确定最大手术用血预定计划(MSBOS)比率以及红细胞输注偏好。两组围手术期目标血红蛋白水平均为10g/dL。在第2组中,异体输血按照2000年1月制定的原则进行,其目标为:(i)更精确地估计手术过程中的失血量并防止血制品的不当使用;(ii)通过输注晶体液和胶体液,在完全消除输血的情况下减少“标准单位输血”的频率;(iii)使用血液成分(红细胞悬液)而非全血。
两组的MSBOS比率均低于2,第1组为1.83,第2组为1.59。第1组所请求和输注的血制品单位中位数分别为2和1,第2组分别为3和2,差异具有统计学意义(p<0.05)。第1组的“标准单位输血”率为28.7%,第2组为18.9%。连续几年中红细胞输注偏好呈现出统计学意义上的增加。第1组红细胞悬液的使用率为29.2%,第2组为95%。
我们的数据表明,由于相关部门之间的良好合作,我们中心为骨科手术制定的输血政策得以成功应用,并达到了国际标准水平。