Faber Christian Emil, Grymer Luisa, Hjorth Tine
Department of Otorhinolaryngology, University Hospital, Aarhus, Denmark.
Rhinology. 2003 Sep;41(3):175-81.
The aim of this study was to determine the severity of side effects and the influence on snoring and the AHI (apnoea-hypopnoea index = number of apnoeas and hypopnoeas per hour recording) of an anterior mandibular positioning device (AMP device) for treatment of snoring and obstructive sleep apnoea. Questionnaires were mailed to a consecutive series of 30 patients who had started treatment with an AMP device. The mean follow-up interval from receiving an AMP device to answering the questionnaire was 22 months. The perceived degree of sore teeth increased statistically significantly (p < 0.01) as a result of the AMP device treatment, but there was no increase in the degree of facial pain, salivation, or temporomandibular joint pain. The AMP device treatment resulted in a statistically significant reduction (p < 0.01) of the mean AHI and of the mean percentage of the recording time with loud snoring (p < 0.05). Twenty-two patients out of 30 were still using the device at the time of follow-up. In conclusion, AMP device treatment was associated with only mild side effects and resulted in a statistically significant reduction of the AHI and of the percentage of the recording time with loud snoring.
本研究的目的是确定用于治疗打鼾和阻塞性睡眠呼吸暂停的下颌前位装置（AMP装置）的副作用严重程度以及对打鼾和呼吸暂停低通气指数（AHI，即每小时记录的呼吸暂停和低通气次数）的影响。向连续30例开始使用AMP装置治疗的患者邮寄了问卷。从收到AMP装置到回答问卷的平均随访间隔为22个月。由于使用AMP装置治疗，牙齿酸痛的感知程度有统计学显著增加（p<0.01），但面部疼痛、流涎或颞下颌关节疼痛程度没有增加。AMP装置治疗使平均AHI和大声打鼾记录时间的平均百分比有统计学显著降低（p<0.01和p<0.05）。随访时30例患者中有22例仍在使用该装置。总之，AMP装置治疗仅伴有轻微副作用，并使AHI和大声打鼾记录时间的百分比有统计学显著降低。
