Bossie M A, Silver P A
Princeton University, New Jersey.
Curr Opin Genet Dev. 1992 Oct;2(5):768-74. doi: 10.1016/s0959-437x(05)80137-6.
Since the first description of signals for nuclear protein localization, studies with yeast have played an important role in our understanding of nuclear protein import. Very recent experiments suggest that new insights into the poorly understood process of RNA export will also emerge from analyses of yeast. Recent advances have facilitated our understanding of protein and RNA exchange between the nucleus and cytoplasm.
自从首次描述核蛋白定位信号以来,对酵母的研究在我们理解核蛋白输入过程中发挥了重要作用。最近的实验表明,对酵母的分析也将为人们对了解甚少的RNA输出过程带来新的见解。最近的进展促进了我们对细胞核与细胞质之间蛋白质和RNA交换的理解。