[The effect of hepatoprotectors on the functional activity of rat hepatocyte mitochondria in in-vitro and in-vivo systems].

In in vitro experiments essential, flacumin, and silibor inhibited the respiratory activity of isolated mitochondria and failed to affect the respiration of hepatocytes in rats at condition 4 by Chance. Essential uncoupled mitochondrial oxidative phosphorylation in the in vitro system. The hepatoprotectors used in ethanol-induced abnormality restored the activity of mitochondrial oxidative phosphorylation of hepatocytes to its level in intact animals.