Pan Erica S, Diep Binh A, Carleton Heather A, Charlebois Edwin D, Sensabaugh George F, Haller Barbara L, Perdreau-Remington Françoise
Department of Pediatrics, San Francisco General Hospital, San Francisco, California 94110, USA.
Clin Infect Dis. 2003 Nov 15;37(10):1384-8. doi: 10.1086/379019. Epub 2003 Oct 17.
Staphylococcus aureus clinical isolates obtained from patients who were inmates of the San Francisco County jail system showed an increase in the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) from 29%, in 1997, to 74%, in 2002; 91% of the MRSA isolates carried staphylococcal chromosomal cassette mec (SCCmec) type IV. Pulsed field gel electrophoresis and multilocus sequence typing demonstrated 2 major clonal groups. One of these clonal groups is genetically indistinguishable from the strain responsible for an outbreak of MRSA in the Los Angeles County jail system in 2002.
从旧金山县监狱系统的囚犯患者中分离出的金黄色葡萄球菌临床菌株显示,耐甲氧西林金黄色葡萄球菌(MRSA)的流行率从1997年的29%上升至2002年的74%;91%的MRSA分离株携带IV型葡萄球菌染色体盒式mec(SCCmec)。脉冲场凝胶电泳和多位点序列分型显示有2个主要克隆群。其中一个克隆群在基因上与2002年洛杉矶县监狱系统中导致MRSA暴发的菌株无法区分。