Ando Soichiro, Kimura Hideki, Iwai Naomichi, Yamamoto Naotaka, Iida Tomohiko
Division of Thoracic Diseases, Chiba Cancer Center, 666-2, Nitona-cho, Chuoh-ku, Chiba 260-8717, Japan.
Nihon Kokyuki Gakkai Zasshi. 2003 Oct;41(10):728-32.
A 53-year-old man was admitted to our hospital for back, left shoulder and upper limb pain. Chest radiography and CT on admission revealed right pleural effusion and a focal plate-like thickening of the major fissure. Pleural effusion cytology revealed adenocarcinoma, which was diagnosed as non-small-cell lung cancer with bone metastasis. The patient suffered from DIC, melena and multiple cerebral infarctions during chemotherapy and died on the eighth day of the second course of chemotherapy. Autopsy revealed a pseudomesotheliomatous adenocarcinoma covering the pleura of the right middle lobe, systemic thromboembolism and vegetations on the aortic valves due to nonbacterial endocarditis. Pseudomesotheliomatous adenocarcinoma of the lung, a rare form of lung cancer, complicated with DIC and nonbacterial endocarditis, is reported.
一名53岁男性因背部、左肩及上肢疼痛入院。入院时胸部X线和CT检查显示右侧胸腔积液及叶间裂局限性片状增厚。胸腔积液细胞学检查发现腺癌,诊断为非小细胞肺癌伴骨转移。患者在化疗期间发生弥散性血管内凝血(DIC)、黑便及多发性脑梗死,在第二个化疗疗程的第8天死亡。尸检发现右中叶胸膜覆盖假间皮瘤样腺癌、系统性血栓栓塞及非细菌性心内膜炎导致的主动脉瓣赘生物。本文报道了1例罕见的肺癌假间皮瘤样腺癌合并DIC及非细菌性心内膜炎的病例。