老年绝经后女性头部瘦体重与局部骨矿物质密度的关系。
Relationship of head lean mass to regional bone mineral density in elderly postmenopausal women.
作者信息
Douchi Tsutomu, Iemura Akiko, Matsuo Takashi, Kuwahata Tomoki, Oki Toshimichi, Yoshimitsu Nobuyuki, Nagata Yukihiro
机构信息
Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
出版信息
Maturitas. 2003 Nov 20;46(3):225-30. doi: 10.1016/s0378-5122(03)00195-6.
OBJECTIVES
This study investigated the relationship of head lean mass to bone mineral density (BMD).
METHOD
Subjects were 102 elderly women (> or =65-years-old) and 123 middle-aged postmenopausal women (<65-years-old) with right-side dominance. Age, height, weight, and years since menopause (YSM) were recorded. Lean mass of the head, arm, trunk, leg, and total body were measured by dual-energy X-ray absorptiometry (DEXA). BMD of the same regions were measured by DEXA.
RESULTS
In elderly women, head lean mass was positively correlated with BMD of the head (r=0.389, P<0.01), left arm (r=0.235, P<0.05), right arm (r=0.280, P<0.05), lumbar spine (L2-4) (r=0.411, P<0.001), pelvis (r=0.490, P<0.001), left leg (r=0.572, P<0.001), right leg (r=0.558, P<0.001), and total body (r=0.529, P<0.001). These relationships remained significant after adjusting for age, height, and YSM. In addition, the strength of correlation of head lean mass with BMD was higher than those of other regional lean mass with respective BMD. In middle-aged women, strength of correlation of head lean mass with BMD was loose (r< or =0.238), while regional lean mass was more correlated with respective regional BMD.
CONCLUSION
Factors related to lifestyle associated with higher (lower) head lean mass may contribute to higher (lower) BMD in elderly postmenopausal women.
目的
本研究调查了头部瘦体重与骨密度（BMD）之间的关系。
方法
研究对象为102名右侧优势的老年女性（≥65岁）和123名中年绝经后女性（<65岁）。记录年龄、身高、体重和绝经年限（YSM）。通过双能X线吸收法（DEXA）测量头部、手臂、躯干、腿部和全身的瘦体重。用DEXA测量相同区域的骨密度。
结果
在老年女性中，头部瘦体重与头部骨密度呈正相关（r = 0.389，P < 0.01），与左臂骨密度呈正相关（r = 0.235，P < 0.05），与右臂骨密度呈正相关（r = 0.280，P < 0.05），与腰椎（L2 - 4）骨密度呈正相关（r = 0.411，P < 0.001），与骨盆骨密度呈正相关（r = 0.490，P < 0.001），与左腿骨密度呈正相关（r = 0.572，P < 0.001），与右腿骨密度呈正相关（r = 0.558，P < 0.001），与全身骨密度呈正相关（r = 0.529，P < 0.001）。在调整年龄、身高和绝经年限后，这些关系仍然显著。此外，头部瘦体重与骨密度的相关性强度高于其他区域瘦体重与各自区域骨密度的相关性强度。在中年女性中，头部瘦体重与骨密度的相关性较弱（r≤0.238），而区域瘦体重与各自区域的骨密度相关性更强。
结论
与较高（较低）头部瘦体重相关的生活方式因素可能导致老年绝经后女性骨密度较高（较低）。
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