丙型肝炎患者的活体供肝肝移植
Living donor liver transplantation in patients with hepatitis C.
作者信息
Zimmerman Michael A, Trotter James F
机构信息
Division of Gastroenterology/Hepatology, University of Colorado Health Sciences Center, Denver, CO 80202, USA.
出版信息
Liver Transpl. 2003 Nov;9(11):S52-7. doi: 10.1053/jlts.2003.50256.
PMID:14586896
Abstract
- Hepatitis C virus (HCV) is the most common indication for living donor liver transplantation (LDLT). 2. Preliminary evidence suggests that HCV may occur earlier and may be more severe in LDLT recipients. However, current data is inconclusive relative to the impact of recurrent HCV on patient and graft survival in LDLT recipients. 3. Potential mechanisms for differences in severity of HCV in LDLT recipients are discussed. 4. LDLT remains a viable treatment option for selected patients with HCV.
摘要
- 丙型肝炎病毒（HCV）是活体肝移植（LDLT）最常见的适应证。2. 初步证据表明，HCV在LDLT受者中可能出现得更早且病情可能更严重。然而，关于复发性HCV对LDLT受者的患者和移植物存活的影响，目前的数据尚无定论。3. 讨论了LDLT受者中HCV严重程度差异的潜在机制。4. 对于选定的HCV患者，LDLT仍然是一种可行的治疗选择。
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