Aleporou-Marinou Vassiliki, Deli Christina, Ninios Yiannis, Agelopoulou Barbara, Marinou Haroula, Patargias Theocharis
Department of Biology, Division of Genetics and Biotechnology, University of Athens, Panepistimiopolis 15701, Athens, Greece.
Biochem Genet. 2003 Aug;41(7-8):235-43. doi: 10.1023/a:1025558318077.
Nuclei from Bactrocera oleae and Ceratitis capitata larvae contain a major protein that shares most of the characteristics of vertebrate high mobility group (HMG) proteins. Proteins are extracted from nuclei with 0.35 M NaCl, are soluble in 5% perchloric acid, are relatively small (molecular weight in the range of 10-16 kDa), and have both a high basic and a high acidic amino acid content. The amino acid constitution of these proteins is similar to that of the HMGB protein family of vertebrates. The proteins cross-react with antibodies raised against the HMGD chromosomal protein of Drosophila melanogaster. The possible relatedness of these proteins to high mobility group proteins is discussed.
