[Plasmin-alpha 2-antiplasmin complexes in blood of patient with lichen planus against the background of other fibrinolysis parameters].

The aim of the present study was to evaluate fibrinolysis in patients with lichen planus. In blood of 20 patients (12 women, 8 men) the levels of tissue type plasminogen activator (t-PA), plasmin-antiplasmin complexes (PAP) and D-dimer were examined. The control group consisted of 37 healthy volunteers. The concentrations of t-PA, PAP and D-dimer were higher in patients with lichen planus in comparison with the control group. It seems that increased level of t-PA antigen in the blood of the patients with lichen planus was the effect of t-PA releasing from endothelial cells. The results of the present study suggest that increased concentrations of t-PA antigen, PAP and D-dimer were the evidence of higher activity of fibrinolysis system in subjects with lichen planus.