Iwan-Zietek I, Zietek Z, Kotschy M, Rość D, Tyloch F
Katedry i Zakładu Patofizjologii, Katedry i Kliniki Urologii Akademii Medycznej, Bydgoszczy.
Pol Tyg Lek. 1996 Feb;51(6-9):91-3.
In 30 patients with prostatic carcinoma a higher of t-PA, a low of PAI-1, alpha 2-antiplasmin and plasminogen activity with increased fibrin degradation products (FDP) level and a short euglobulin lysis time (ELT) were observed. Following surgery a further increased of fibrinolytic activity occurred. The activity of t-PA and PAI-1 were higher than before operation. Apart from that we observed a decreased of plasminogen and alpha 2-AP with further increased level of FDP. On 5-th day the values of examined parameters were similar as before the operation.
在30例前列腺癌患者中，观察到组织型纤溶酶原激活物（t-PA）水平较高、纤溶酶原激活物抑制剂-1（PAI-1）、α2-抗纤溶酶和纤溶酶原活性较低，纤维蛋白降解产物（FDP）水平升高，优球蛋白溶解时间（ELT）缩短。手术后纤溶活性进一步增强。t-PA和PAI-1的活性高于手术前。除此之外，我们观察到纤溶酶原和α2-抗纤溶酶减少，FDP水平进一步升高。在第5天，检测参数的值与手术前相似。
