Mahajan K K, Mahajan S K, Mishra N
Department of Physiology Medical College, Rohtak.
Indian J Chest Dis Allied Sci. 1992 Apr-Jun;34(2):77-83.
Measurement of lung transfer factor for CO (TLCO) and its constituent components, viz. diffusion capacity across alveolar capillary membrane (Dm) and instant pulmonary capillary blood volume (Vc) were undertaken in 120 healthy non-smoker males by single breath technique. All the three parameters (TLCO, Dm, Vc) showed direct negative correlation with age. While TLCO and Dm showed a significant direct positive correlation with height, there was no correlation between VC and height. The degree of correlation increased when both age and height were used together than either of them alone for prediction of TLCO120. The prediction formulae (TLCO120 = 3.8 + 21 H (m)-0.308 A) using both age and height has regression value (R) of 0.6479 (p < 0.001).
采用单次呼吸法对120名健康非吸烟男性进行了一氧化碳肺转移因子（TLCO）及其组成成分，即肺泡毛细血管膜弥散能力（Dm）和瞬间肺毛细血管血容量（Vc）的测量。所有这三个参数（TLCO、Dm、Vc）均与年龄呈直接负相关。虽然TLCO和Dm与身高呈显著直接正相关，但VC与身高之间无相关性。当同时使用年龄和身高来预测TLCO120时，相关性程度比单独使用其中任何一个因素时都有所增加。使用年龄和身高的预测公式（TLCO120 = 3.8 + 21H（米）- 0.308A）的回归值（R）为0.6479（p < 0.001）。
