Verweij J, van Oosterom A T
Department of Medical Oncology, Rotterdam Cancer Institute, Daniel den Hoed Kliniek, The Netherlands.
J Belge Radiol. 1992 Aug;75(4):258-64.
Soft tissue sarcomas are rare tumors including many histological subtypes. They are pre-eminently tumors for which the multidisciplinary approach to treatment is of utmost importance. The two most frequently applied staging systems both require experienced assessment of radiology and pathology, and stage is a prominent prognostic factor for survival that guides the choice of treatment modalities. For primary treatment radical surgery is still the backbone. In many instances postoperative radiotherapy is a valuable and often necessary complementary treatment. The role of preoperative radiotherapy and/or chemotherapy needs to be defined although preliminary results are interesting. Chemotherapy as an adjunct to surgery should still be considered investigational. In metastatic disease "standard" chemotherapy has a definitive though moderate activity, but recent data on dose-intensified chemotherapy suggest that results may be further improved.
软组织肉瘤是罕见肿瘤，包括许多组织学亚型。它们是多学科治疗方法极为重要的肿瘤。两种最常用的分期系统都需要放射学和病理学方面的经验丰富的评估，分期是指导治疗方式选择的生存预后的重要因素。对于初始治疗，根治性手术仍然是基础。在许多情况下，术后放疗是一种有价值且常常必要的辅助治疗。尽管初步结果令人关注，但术前放疗和/或化疗的作用仍需明确。作为手术辅助手段的化疗仍应视为试验性的。在转移性疾病中，“标准”化疗虽有明确但适度的活性，不过关于剂量强化化疗的最新数据表明结果可能会进一步改善。
