[乳腺导管原位癌的保守性手术]

[Conservative surgery for ductal carcinoma in situ of the breast].

作者信息

Tersigni R, Mencacci R, Alessandroni L, Baiano G, Mardarella C, Parisi A

机构信息

Struttura Complessa di Chirurgia Generale 1 Flajani, Azienda Ospedaliera, San Camillo-Forlanini, Roma, Italy.

出版信息

Minerva Chir. 2003 Aug;58(4):563-9.

PMID:14603170

Abstract

BACKGROUND

The conservative surgery is considered currently the treatment of choice for the carcinoma of the breast in the initial stage.

METHODS

From 1993 to the 2000, 46 patients (median age 52 years) affected by intraductal carcinoma of the breast, have been submitted to surgical intervention. In 10 cases (21,7%) a palpable mass was observed (mean dimension of 1.3 cm). In 36 cases (78.3%) non palpable lesions were identified by mammography (26 microcalcifications and 10 non palpable masses). All patients have been treated after stereotactic preoperatory mammographic localization of the lesions. 15 simple mastectomies, 11 mammary resections without radiotherapy and 20 mammary resections followed by radiotherapy have been performed. No patient was submitted to axillary dissection. The radiotherapy has been administered with a boost of 50 Gy on the breast.

RESULTS

At a 36 months median follow-up all the patients are alive and no local recurrence or distant metastases has been observed.

CONCLUSIONS

The treatment of choice is the local resection of neoplasm followed by radiotherapy.

摘要

背景

目前，保守手术被认为是早期乳腺癌的首选治疗方法。

方法

1993年至2000年，46例乳腺导管内癌患者（中位年龄52岁）接受了手术干预。10例（21.7%）可触及肿块（平均大小1.3厘米）。36例（78.3%）通过乳房X线摄影发现不可触及病变（26例微钙化和10例不可触及肿块）。所有患者均在病变的立体定向术前乳房X线摄影定位后接受治疗。进行了15例单纯乳房切除术、11例未进行放疗的乳腺切除术和20例乳腺切除术后放疗。没有患者接受腋窝清扫术。放疗时对乳房追加50 Gy。