• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[日常中的酒精性患者]

[The alcoholic patient in the daily routine].

作者信息

Breuer Jan-Philipp, Neumann Tim, Heinz Andreas, Kox Wolfgang J, Spies Claudia

机构信息

Klinik für Anästhesiologie und operative Intensivmedizin, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Gemeinsame Einrichtung von Freier Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Deutschland.

出版信息

Wien Klin Wochenschr. 2003 Sep 30;115(17-18):618-33. doi: 10.1007/BF03040467.

DOI:10.1007/BF03040467
PMID:14603733
Abstract

Chronic alcohol abuse is of significant clinical and economic relevance. A major part of internal medical pathology is associated with chronic alcoholism. 50% of all accidents with subsequent traumatic injuries are related to alcohol intake. Patients who are chronic alcohol abusers have prolonged hospital stays and substantial increases in postoperative morbidity. A sophisticated diagnosis of alcoholism within standard clinical routine is often difficult, and in most cases the treatment of alcohol-related diseases and complications is protracted and requires increased energy expenditure by the treating physicians. In surgical patients, chronic alcohol abuse is associated with a 3- to 4-fold risk of infections, sepsis, cardiac and bleeding complications. Therefore, the patients themselves, along with the general practitioner and an in-hospital interdisciplinary team should cooperate in medical and operative treatment in order to attain better clinical outcome. Each patient history should include a detailed assessment of the quantity of daily alcohol intake. Alcoholic diagnostic regimens including questionnaires (i.e. CAGE, AUDIT) in combination with specific laboratory markers (CDT, GGT, MCV), if implemented, could prove valuable, especially in cases where major surgical procedures are considered. Strict abstinence by alcoholic patients with organ pathology in medical and elective surgical settings as well as the prophylactic treatment of pre-operative alcohol withdrawal appear to be useful strategies to reduce the risk of complications. Short-term interventions are associated with reduced alcohol intake and decreased incidence of re-trauma. Considering the clinical relevance of alcohol abuse, sufficient screening, interventions, and open approaches to address alcohol problems should be important components of the daily clinical routine in outpatient clinics, emergency rooms, in GPs' offices and in general hospitals.

摘要

长期酗酒具有重大的临床和经济意义。内科病理学的很大一部分与慢性酒精中毒有关。所有后续有创伤性损伤的事故中,50%与饮酒有关。慢性酗酒患者住院时间延长,术后发病率大幅增加。在标准临床常规中对酒精中毒进行精确诊断往往很困难,而且在大多数情况下,与酒精相关疾病和并发症的治疗过程漫长,需要治疗医生付出更多精力。在外科手术患者中,慢性酗酒会使感染、败血症、心脏和出血并发症的风险增加3至4倍。因此,患者本人应与全科医生及医院内的跨学科团队合作进行药物和手术治疗,以获得更好的临床效果。每份患者病历都应包括对每日饮酒量的详细评估。如果实施包括问卷(如CAGE、AUDIT)以及特定实验室指标(CDT、GGT、MCV)在内的酒精诊断方案,可能会很有价值,尤其是在考虑进行大型外科手术的情况下。患有器官病变的酗酒患者在接受药物治疗和择期手术时严格戒酒,以及对术前酒精戒断进行预防性治疗,似乎是降低并发症风险的有效策略。短期干预与饮酒量减少和再次受伤发生率降低有关。鉴于酗酒的临床相关性,充分的筛查、干预以及解决酒精问题的开放方法应成为门诊诊所、急诊室、全科医生办公室和综合医院日常临床工作的重要组成部分。

相似文献

1
[The alcoholic patient in the daily routine].[日常中的酒精性患者]
Wien Klin Wochenschr. 2003 Sep 30;115(17-18):618-33. doi: 10.1007/BF03040467.
2
[The relevance of CDT (carbohydrate-deficient transferrin). Preoperative diagnosis of chronic alcohol abuse in intensive care patients following elective tumor resection].[缺糖转铁蛋白(CDT)的相关性。择期肿瘤切除术后重症监护患者慢性酒精滥用的术前诊断]
Anaesthesist. 1994 Jul;43(7):447-53. doi: 10.1007/s001010050077.
3
Alcohol abuse and postoperative morbidity.酒精滥用与术后发病率。
Dan Med Bull. 2003 May;50(2):139-60.
4
Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis.因酒精问题前往医院就诊的次数可预测后续发生酒精性肝硬化的风险。
Scand J Public Health. 2019 Jun;47(4):417-419. doi: 10.1177/1403494818763436. Epub 2018 Mar 10.
5
The Utility of Commonly Used Laboratory Tests to Screen for Excessive Alcohol Use in Clinical Practice.常用实验室检查在临床实践中筛查过度饮酒的效用。
Alcohol Clin Exp Res. 2015 Aug;39(8):1493-500. doi: 10.1111/acer.12780. Epub 2015 Jun 25.
6
[Diagnostic value of gamma glutamyl transpeptidase and the mean corpuscular volume in chronic hepatitis of alcoholic etiology].γ-谷氨酰转肽酶和平均红细胞体积在酒精性病因慢性肝炎中的诊断价值
Minerva Med. 1995 Oct;86(10):395-402.
7
Validity of carbohydrate-deficient transferrin (%CDT), gamma-glutamyltransferase (gamma-GT) and mean corpuscular erythrocyte volume (MCV) as biomarkers for chronic alcohol abuse: a study in patients with alcohol dependence and liver disorders of non-alcoholic and alcoholic origin.碳水化合物缺乏转铁蛋白(%CDT)、γ-谷氨酰转移酶(γ-GT)和平均红细胞体积(MCV)作为慢性酒精滥用生物标志物的有效性:一项针对酒精依赖患者以及非酒精性和酒精性肝病患者的研究
Addiction. 2005 Oct;100(10):1477-86. doi: 10.1111/j.1360-0443.2005.01216.x.
8
ACG Clinical Guideline: Alcoholic Liver Disease.ACG 临床指南:酒精性肝病。
Am J Gastroenterol. 2018 Feb;113(2):175-194. doi: 10.1038/ajg.2017.469. Epub 2018 Jan 16.
9
[Laboratory diagnosis of visceral disorders in alcoholism].[酒精中毒内脏疾病的实验室诊断]
Klin Med (Mosk). 1990 Jan;68(1):26-35.
10
Identification and management of acute alcohol intoxication.急性酒精中毒的识别与处理。
Eur J Intern Med. 2023 Feb;108:1-8. doi: 10.1016/j.ejim.2022.08.013. Epub 2022 Aug 16.

引用本文的文献

1
Impact of blood alcohol concentration on hematologic and serum chemistry parameters in trauma patients: Analysis of data from a high-volume level 1 trauma center.血液酒精浓度对创伤患者血液学和血清化学参数的影响:来自一家大型一级创伤中心的数据分析。
Int J Crit Illn Inj Sci. 2021 Jan-Mar;11(1):18-24. doi: 10.4103/IJCIIS.IJCIIS_112_20. Epub 2021 Mar 27.
2
Perioperative alcohol cessation intervention for postoperative complications.围手术期戒酒干预对术后并发症的影响
Cochrane Database Syst Rev. 2018 Nov 8;11(11):CD008343. doi: 10.1002/14651858.CD008343.pub3.
3
Alcohol drinking does not affect postoperative surgical site infection or anastomotic leakage: a systematic review and meta-analysis.

本文引用的文献

1
The incidence of alcohol-related problems and the risk of alcohol withdrawal in a general hospital population.综合医院人群中酒精相关问题的发生率及酒精戒断风险。
Drug Alcohol Rev. 1995;14(1):49-54. doi: 10.1080/09595239500185051.
2
[Clinical aspects of the so-called symptomatic psychoses].[所谓症状性精神病的临床方面]
Dtsch Med Wochenschr. 1956 Aug 24;81(34):1345-9. doi: 10.1055/s-0028-1115128.
3
Oral topiramate for treatment of alcohol dependence: a randomised controlled trial.口服托吡酯治疗酒精依赖:一项随机对照试验。
饮酒并不影响术后手术部位感染或吻合口漏:系统评价和荟萃分析。
J Gastrointest Surg. 2014 Feb;18(2):414-25. doi: 10.1007/s11605-013-2275-5. Epub 2013 Jul 9.
4
Learning by doing: a novel approach to improving general practitioners' diagnostic skills for common mental disorders.通过实践学习:一种提高全科医生对常见精神障碍诊断技能的新方法。
Wien Klin Wochenschr. 2007;119(3-4):117-23. doi: 10.1007/s00508-006-0702-2.
5
Another 'soberade' on the market: does Outox keep its promise?市场上的另一种“解酒产品”:Outox能兑现承诺吗?
Wien Klin Wochenschr. 2007;119(3-4):104-11. doi: 10.1007/s00508-006-0705-z.
6
[Alcohol use disorder: risks in anesthesia and intensive care medicine].[酒精使用障碍:麻醉与重症医学中的风险]
Internist (Berl). 2006 Apr;47(4):332, 334-6, 338, passim. doi: 10.1007/s00108-006-1588-9.
Lancet. 2003 May 17;361(9370):1677-85. doi: 10.1016/S0140-6736(03)13370-3.
4
Management of drug and alcohol withdrawal.药物和酒精戒断的管理。
N Engl J Med. 2003 May 1;348(18):1786-95. doi: 10.1056/NEJMra020617.
5
The Royal College of Physicians report on alcohol: guidelines for managing Wernicke's encephalopathy in the accident and Emergency Department.皇家内科医师学院关于酒精的报告:急诊科韦尼克脑病管理指南。
Alcohol Alcohol. 2002 Nov-Dec;37(6):513-21. doi: 10.1093/alcalc/37.6.513.
6
Hypokalaemia in alcoholic patients.酒精性患者的低钾血症
Drug Alcohol Rev. 2002 Mar;21(1):73-6. doi: 10.1080/09595230220119282a.
7
Suppression of interleukin-6 to interleukin-10 ratio in chronic alcoholics: association with postoperative infections.慢性酒精中毒患者白细胞介素-6与白细胞介素-10比值的抑制:与术后感染的关联
Intensive Care Med. 2002 Mar;28(3):285-92. doi: 10.1007/s00134-001-1199-9. Epub 2002 Feb 2.
8
Effects of alcohol on the heart.酒精对心脏的影响。
Curr Opin Crit Care. 2001 Oct;7(5):337-43. doi: 10.1097/00075198-200110000-00004.
9
[Stress management in heart diseases, obesity, nicotine and alcohol use].[心脏病、肥胖症、尼古丁及酒精使用方面的压力管理]
Wien Klin Wochenschr. 2001 Dec 17;113(23-24):947-53.
10
[Craving for alcohol and prevention of relapse].[对酒精的渴望与复发预防]
Wien Klin Wochenschr. 2001 Oct 15;113(19):717-26.