妊娠期间作为多发性内分泌腺瘤病IIa一部分的嗜铬细胞瘤非典型表现。
Atypical presentation of pheochromocytoma as part of multiple endocrine neoplasia IIa in pregnancy.
作者信息
Ahn Jennifer T, Hibbard Judith U, Chapa Jeff B
机构信息
Department of Obstetrics and Gynecology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.
出版信息
Obstet Gynecol. 2003 Nov;102(5 Pt 2):1202-5. doi: 10.1016/s0029-7844(03)00627-6.
BACKGROUND
Pheochromocytoma in pregnancy is extremely dangerous, especially when unrecognized, and can present alone or as part of a multineoplastic syndrome. Hypertension, its hallmark, is not present in all cases, particularly in women with multiple endocrine neoplasia type IIa.
CASE
We report a gravida with undiagnosed multiple endocrine neoplasia IIa who presented initially with peripartum cardiomyopathy but was diagnosed with an underlying pheochromocytoma. Once recognized and treated with appropriate alpha-adrenergic blockade, her condition reversed quickly.
CONCLUSION
Physicians should be aware that pheochromocytoma can present as cardiovascular collapse rather than just hypertension.
背景
妊娠期嗜铬细胞瘤极其危险，尤其是在未被识别的情况下，它可单独出现或作为多肿瘤综合征的一部分出现。高血压是其标志性症状，但并非在所有病例中都出现，特别是在患有IIa型多发性内分泌腺瘤病的女性中。
病例
我们报告了一名患有未确诊的IIa型多发性内分泌腺瘤病的孕妇，她最初表现为围产期心肌病，但最终被诊断出患有潜在的嗜铬细胞瘤。一旦确诊并接受适当的α-肾上腺素能阻滞剂治疗，她的病情迅速好转。
结论
医生应意识到嗜铬细胞瘤可能表现为心血管衰竭而非仅仅是高血压。
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