Park Eun-sung, Jo Seona, Seong Je-kyung, Nam Tchi-chou, Yang Il-suk, Choi Min-cheol, Yoon Yeo-sung
Department of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, San 56-1, Shilim-dong, Gwanak-gu, Seoul 151-742, Korea.
J Vet Sci. 2003 Aug;4(2):125-8.
The effect of acupuncture in the treatment of young pigs with induced enteropathogenic Escherichia coli diarrhea was histopathologically evaluated by routine hematoxylin and eosin stain. Thirty two pigs weighed 4-5 kg and aged 21 days old were used in this study. The animals with diarrhea were treated with traditional acupuncture, or enrofloxacin. In the group treated with traditional acupuncture, acupoint GV1 (Jiaochao) was used and in the group treated with antibiotics, enrofloxacin was injected intramuscularly. Ten pigs were inoculated with E. coli, but were not treated and served as nontreated control group. At postinoculation day 6, all pigs of the acupuncture and antibiotic treated groups recovered from diarrhea. In the ascending and descending colons of the nontreated control group, severe infiltration of inflammatory cells in the lamina propria was observed and in the fundic stomach, destruction of the fundic gland architecture and necrotic lesions were observed, however, in the same sites of the acupuncture and antibiotics treated groups, the mucosae of the colon and stomach were relatively similar to those of the normal group. These results indicate that acupuncture treatment is effective in controlling induced E. coli diarrhea in pigs at its early stage.
通过常规苏木精和伊红染色，对针灸治疗人工诱导的仔猪致病性大肠杆菌腹泻的效果进行组织病理学评估。本研究使用了32头体重4 - 5千克、21日龄的仔猪。对腹泻的动物采用传统针灸或恩诺沙星进行治疗。在传统针灸治疗组中，使用穴位GV1（交巢），抗生素治疗组则肌肉注射恩诺沙星。10头仔猪接种大肠杆菌但未治疗，作为未治疗对照组。接种后第6天，针灸治疗组和抗生素治疗组的所有仔猪腹泻均痊愈。在未治疗对照组的升结肠和降结肠中，观察到固有层有严重的炎性细胞浸润，在胃底，观察到胃底腺结构破坏和坏死病变，然而，在针灸治疗组和抗生素治疗组的相同部位，结肠和胃的黏膜与正常组相对相似。这些结果表明，针灸治疗在控制仔猪早期人工诱导的大肠杆菌腹泻方面是有效的。
