Chervenak Frank A, McCullough Laurence B
Department of Obstetrics and Gynecology, New York Presbyterian Hospital, 525 East 68th Street--J130, New York, NY 10021, USA.
Curr Womens Health Rep. 2003 Dec;3(6):505-9.
In this chapter, we address ethical issues in research involving fetuses and pregnant women, with particular attention to the emerging issue of gene-transfer research. Ethical analyses and arguments are based on the concept of the fetus as a patient. The implications of this concept for the ethics of fetal research are identified. The discussion of gene-transfer research extends those implications to address issues concerning informed consent, assessment of potential fetal and neonatal morbidity in study design, prenatal diagnosis after gene transfer, selection criteria based on abortion preference, science by press conference, germline risks, and public oversight.
在本章中，我们探讨涉及胎儿和孕妇的研究中的伦理问题，尤其关注基因转移研究这一新兴问题。伦理分析和论证基于将胎儿视为患者的概念。确定了这一概念对胎儿研究伦理的影响。对基因转移研究的讨论扩展了这些影响，以解决有关知情同意、研究设计中潜在胎儿和新生儿发病率的评估、基因转移后的产前诊断、基于堕胎偏好的选择标准、通过新闻发布会进行科学研究、种系风险以及公众监督等问题。
