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美国年轻成年人全国样本中情绪障碍的患病率。

Prevalence of mood disorders in a national sample of young American adults.

作者信息

Jonas Bruce S, Brody Debra, Roper Margaret, Narrow William E

机构信息

Centers for Disease Control and Prevention National Center for Health Statistics Office of Analysis, Epidemiology & Health Promotion, Room 6433, 3311 Toledo Road, Hyattsville, MD 20782, USA.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2003 Nov;38(11):618-24. doi: 10.1007/s00127-003-0682-8.

Abstract

BACKGROUND

Availability of nationally representative mood disorder prevalence estimates in the United States, based on structured psychiatric interviews is limited. This report estimates overall lifetime prevalence of major depressive episode, dysthymia, and bipolar disorder using the Third National Health and Nutrition Examination Survey (NHANES III) and compares these estimates to the Epidemiologic Catchment Area Study (ECA) conducted 10 years earlier. Additionally, prevalence estimate breakdowns by selected sociodemographic and health characteristics are investigated.

METHODS

NHANES III, conducted from 1988 to 1994, is a large nationally representative cross-sectional sample of the United States. A population-based sample of 8,602 men and women 17-39 years of age were eligible to participate, of whom 7,667 (89.1 %) completed interviews. Mood disorder assessments came from the Diagnostic Interview Schedule (DIS) administered as one component of the NHANES III.

RESULTS

Lifetime prevalence estimates were assessed for six mood measures: 1) major depressive episode (MDE) 8.6%, 2) major depressive episode with severity (MDE-s) 7.7%, 3) dysthymia 6.2%, 4) MDE-s with dysthymia 3.4%, 5) any bipolar disorder 1.6%, and 6) any mood disorder 11.5%. All estimates except for MDE and MDE-s were significantly higher than comparable ECA estimates.

CONCLUSIONS

These data provide recent national prevalence estimates. Based on their overall magnitudes, subgroup excesses, and observed increases compared to the ECA, continued monitoring of these estimates is warranted.

摘要

背景

在美国,基于结构化精神病学访谈得出的具有全国代表性的情绪障碍患病率估计数据有限。本报告使用第三次全国健康与营养检查调查(NHANES III)估算重度抑郁发作、心境恶劣和双相情感障碍的终生总体患病率,并将这些估计值与10年前进行的流行病学集水区研究(ECA)进行比较。此外,还调查了按选定的社会人口学和健康特征划分的患病率估计细目。

方法

NHANES III于1988年至1994年进行,是美国一个具有全国代表性的大型横断面样本。以人口为基础的8602名17 - 39岁男女样本有资格参与,其中7667人(89.1%)完成了访谈。情绪障碍评估来自作为NHANES III一部分进行的诊断访谈表(DIS)。

结果

对六种情绪测量指标的终生患病率进行了评估:1)重度抑郁发作(MDE)8.6%,2)伴有严重程度的重度抑郁发作(MDE - s)7.7%,3)心境恶劣6.2%,4)伴有心境恶劣的MDE - s 3.4%,5)任何双相情感障碍1.6%,6)任何情绪障碍11.5%。除MDE和MDE - s外,所有估计值均显著高于ECA的可比估计值。

结论

这些数据提供了近期的全国患病率估计值。基于其总体规模、亚组超额情况以及与ECA相比观察到的增加情况,有必要继续监测这些估计值。

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