Ruiz G, García Rodríguez J, Güerri M L, González A
Servicio de Microbiología y Parasitología Clínica, Hospital Universitario La Paz, Paseo de la Castellana no. 261, 28046 Madrid, Spain.
Clin Microbiol Infect. 2003 Sep;9(9):919-23. doi: 10.1046/j.1469-0691.2003.00671.x.
To study clinical features of skeletal tuberculosis diagnosed in our laboratory over the last 10 years.
We carried out a retrospective observational study of 26 patients with osteoarticular tuberculosis recording clinical and microbiological data.
Pain was the main clinical presentation. The median time from the onset of symptoms to the diagnosis was 8 months. Synovial fluid was the most common sample obtained. Bone disease and previous or concurrent pulmonary tuberculosis were the most important predisposing factors. The tuberculin test reaction was positive in 83.3% of the patients. The outcome was favorable in 69% of the patients. Weight-bearing joints were the most commonly involved sites.
A high degree of suspicion is still needed to avoid a delayed diagnosis that might complicate the outcome.
研究过去10年在我们实验室诊断的骨结核临床特征。
我们对26例骨关节结核患者进行了回顾性观察研究,记录临床和微生物学数据。
疼痛是主要临床表现。从症状出现到诊断的中位时间为8个月。滑膜液是最常获取的样本。骨病以及既往或并发肺结核是最重要的诱发因素。83.3%的患者结核菌素试验反应呈阳性。69%的患者预后良好。负重关节是最常受累部位。
仍需要高度怀疑以避免延迟诊断,否则可能使病情复杂化。