Goldstein F W, Kitzis M D
Clin Microbiol Infect. 2003 Aug;9(8):761-5. doi: 10.1046/j.1469-0691.2003.00734.x.
The number of reports concerning vancomycin-resistant Staphylococcus aureus is much higher than the number of true resistant strains or unexpected clinical failures. Many confounding factors, including inadequate serum levels, severely ill patients, foreign devices or undrained abscesses, are more likely to be responsible for the clinical failures than resistance to vancomycin.
关于耐万古霉素金黄色葡萄球菌的报告数量远高于真正的耐药菌株数量或意外的临床治疗失败数量。许多混杂因素,包括血清浓度不足、重症患者、体内有异物装置或未引流的脓肿,比耐万古霉素更有可能是导致临床治疗失败的原因。