Bernatoniene Jurga, Bernatoniene Rūta, Jakstas Valdas, Malinauskas Faustas, Brusokas Valdemaras
Faculty of Pharmacy, Kaunas University of Medicine, Kaunas, Lithuania.
Medicina (Kaunas). 2003;39 Suppl 2:76-9.
This article deals with the production of the tincture of Ginkgo biloba leaves, Crataegus fruits and Leonurus herbs while selecting an extractant, the size of particles in a raw material and possible methods of extraction. The optimal composition of ethanol 70%, the particle size of Ginkgo biloba leaves and Crataegus fruits 2-3 mm of Leonurus herbs. The method of production--percolation, the flow speed 0.5 ml/min. The tincture was analyzed at determination of the sum of flavonoids in terms of quercetin, dry residue, relative density, ethanol concentration. The quality of the tincture was evaluated by high-pressure liquid chromatography and spectrophotometry. The stability of the tincture and its expiry date were fixed.
本文探讨了银杏叶、山楂果和益母草酊剂的生产,涉及萃取剂的选择、原料颗粒大小以及可能的萃取方法。最佳乙醇成分为70%,银杏叶和山楂果的颗粒大小为2 - 3毫米,益母草为草本。生产方法为渗漉法,流速为0.5毫升/分钟。对酊剂进行了分析,测定了以槲皮素计的总黄酮含量、干残渣、相对密度、乙醇浓度。通过高压液相色谱法和分光光度法对酊剂质量进行评估。确定了酊剂的稳定性及其保质期。