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桥小脑角脑膜瘤。临床特征与手术治疗

Cerebellopontine angle meningiomas. Clinical features and surgical treatment.

作者信息

Gerganov V, Bussarsky V, Romansky K, Popov R, Djendov S, Dimitrov I

机构信息

Department of Neurosurgery, Alexander's University Hospital, Sofia, Bulgaria.

出版信息

J Neurosurg Sci. 2003 Sep;47(3):129-35; discussion 135.

Abstract

AIM

The aim of this study is to present the clinical picture of patients with cerebellopontine angle meningiomas and analyze the results of their operative treatment.

METHODS

A retrospective study of patients with cerebellopontine angle meningiomas operated consecutively in our department over an 11-year period has been carried out. Data regarding their clinical features, surgical treatment, morbidity, mortality and outcome have been analyzed. Forty-four patients with cerebellopontine angle meningiomas were operated during the period 1991-2001 (intervention: tumor removal via the retrosigmoid suboccipital approach).

MAIN OUTCOME MEASURES

clinical condition, MRI/ CT imaging.

RESULTS

The median duration of symptoms prior to diagnosis was 44.5 months. The most frequent initial complaints were hearing loss, tinnitus and headache. Most frequent symptoms and signs at presentation were cerebellar, followed by hearing loss and trigeminal nerve symptoms. In 98% of the cases the operative approach used was the retrosigmoidal suboccipital. Total tumor removal was achieved in 55%. After total tumor removal no recurrences have been observed. The mortality rate was 2%.

CONCLUSION

The application of different classification schemes complicates the comparison between published series. The outcome depends on their location, consistency, size and relation to the surrounding neurovascular structures. In our experience the retrosigmoid suboccipital approach is most appropriate for their surgical treatment. It offers the possibility to remove completely even large meningiomas and avoids the risk of recurrences.

摘要

目的

本研究旨在呈现桥小脑角脑膜瘤患者的临床表现,并分析其手术治疗结果。

方法

对在我们科室连续11年接受手术治疗的桥小脑角脑膜瘤患者进行了一项回顾性研究。分析了有关他们临床特征、手术治疗、发病率、死亡率及预后的数据。1991年至2001年期间,对44例桥小脑角脑膜瘤患者进行了手术(干预措施:经乙状窦后枕下入路切除肿瘤)。

主要观察指标

临床状况、MRI/CT成像。

结果

诊断前症状的中位持续时间为44.5个月。最常见的初始症状为听力丧失、耳鸣和头痛。就诊时最常见的症状和体征为小脑症状,其次是听力丧失和三叉神经症状。98%的病例采用乙状窦后枕下入路。55%的病例实现了肿瘤全切。肿瘤全切后未观察到复发情况。死亡率为2%。

结论

不同分类方案的应用使已发表系列研究之间的比较变得复杂。预后取决于肿瘤的位置、质地、大小以及与周围神经血管结构的关系。根据我们的经验,乙状窦后枕下入路最适合其手术治疗。它甚至为完全切除大型脑膜瘤提供了可能,并避免了复发风险。

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