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The multi-KH protein vigilin associates with free and membrane-bound ribosomes.
Cell Mol Life Sci. 2003 Oct;60(10):2219-27. doi: 10.1007/s00018-003-3235-0.
2
Vigilin is co-localized with 80S ribosomes and binds to the ribosomal complex through its C-terminal domain.
Int J Biochem Cell Biol. 2004 Jul;36(7):1306-18. doi: 10.1016/j.biocel.2003.11.006.
3
Drosophila vigilin, DDP1, localises to the cytoplasm and associates to the rough endoplasmic reticulum.
Biochim Biophys Acta. 2011 Jan;1809(1):46-55. doi: 10.1016/j.bbagrm.2010.10.005. Epub 2010 Oct 28.
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Protein synthesis of eucaryotic cells could be decreased by antisense-DNA of the multi KH domain protein vigilin.
Int J Mol Med. 2003 Jul;12(1):35-43.
5
In vitro genetic analysis of the RNA binding site of vigilin, a multi-KH-domain protein.
Mol Cell Biol. 1998 Jul;18(7):3991-4003. doi: 10.1128/MCB.18.7.3991.
6
tRNA is entrapped in similar, but distinct, nuclear and cytoplasmic ribonucleoprotein complexes, both of which contain vigilin and elongation factor 1 alpha.
Biochem J. 1998 Feb 1;329 ( Pt 3)(Pt 3):615-21. doi: 10.1042/bj3290615.
7
Immunocytochemical localization of vigilin, a tRNA-binding protein, after cell fractionation and within the exocrine pancreatic cell of the rat.
Ann Anat. 1996 Aug;178(4):331-5. doi: 10.1016/S0940-9602(96)80086-0.
8
Export and transport of tRNA are coupled to a multi-protein complex.
Biochem J. 2000 Feb 15;346 Pt 1(Pt 1):107-15.
9
Vigilin, a ubiquitous protein with 14 K homology domains, is the estrogen-inducible vitellogenin mRNA 3'-untranslated region-binding protein.
J Biol Chem. 1997 May 9;272(19):12249-52. doi: 10.1074/jbc.272.19.12249.
10
RNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesis.
Nucleic Acids Res. 2003 Oct 1;31(19):5644-53. doi: 10.1093/nar/gkg768.
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Vigilin interacts with signal peptide peptidase.
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Posttranscriptional suppression of proto-oncogene c-fms expression by vigilin in breast cancer.
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