Miki Hirofumi, Tamura Shigeyuki, Wada Hiroshi, Kozuma Yasuyuki, Kittaka Nobuyoshi, Kim Tyuwan, Takiuchi Daisuke, Aihara Tomohiko, Sugimoto Keiji, Fukunaga Mutsumi, Ozato Hiroki, Tomita Naohiro, Takatsuka Yuichi
Dept. of Surgery, Kansai Rosai Hospital.
Gan To Kagaku Ryoho. 2003 Oct;30(11):1661-4.
A 66-year-old male was diagnosed with advanced gastric cancer with pylorus stenosis, and the first abdominal computed tomography (CT) revealed a large amount of ascites. A staging laparoscopy revealed peritoneal dissemination and positive cytology for numerous amounts of ascites (s-T3(SE), N0, M0, p(+), cy(+), H0, s-Stage IV). The patient received TS-1 orally and paclitaxel administered to the peritoneal cavity. After finishing the second course of the combined chemotherapy, second-look staging laparoscopy was performed, which showed the disappearance of peritoneal dissemination and negative cytology. Chemotherapy combined with oral TS-1 and paclitaxel administered to the peritoneal cavity might be an effective strategy against advanced gastric cancer with peritoneal dissemination.
一名66岁男性被诊断为晚期胃癌伴幽门狭窄，首次腹部计算机断层扫描（CT）显示大量腹水。分期腹腔镜检查发现腹膜播散，大量腹水的细胞学检查呈阳性（s-T3(SE)，N0，M0，p(+)，cy(+)，H0，s-分期IV期）。患者口服替吉奥并向腹腔内注射紫杉醇。在完成第二疗程的联合化疗后，进行了二次分期腹腔镜检查，结果显示腹膜播散消失且细胞学检查呈阴性。口服替吉奥与向腹腔内注射紫杉醇联合化疗可能是治疗伴有腹膜播散的晚期胃癌的有效策略。
