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成人型卵黄样营养不良的光学相干断层扫描

Optical coherence tomography of adult-onset vitelliform dystrophy.

作者信息

Hayami M, Decock Chr, Brabant P, Van Kerckhoven W, Lafaut B A, De Laey J J

机构信息

Department of Ophthalmology, Ghent University Hospital.

出版信息

Bull Soc Belge Ophtalmol. 2003(289):53-61.

Abstract

PURPOSE

To report the cross-sectional structure of the retina and choroid in eyes with adult-onset vitelliform macular dystrophy as obtained by optical coherence tomography (OCT).

METHODS

Seven patients with adult-onset vitelliform macular dystrophy and one patient with Best disease were examined by fundoscopy, fluorescein and indocyanine green angiography and OCT. Three patients underwent also electro-oculography.

RESULTS

  1. Seven cases with adult-onset vitelliform macular dystrophy showed a well-circumscribed elevation of a highly reflective band, corresponding to the retinal pigment epithelium 2. In these 7 patients, the space below this band was inhomogeneous and moderately reflective. 3. Four cases out of 7 had a well defined posterior boundary. 4. The patient with Best disease disclosed a different aspect on OCT, although the contour of the lesion was similar to the others.

CONCLUSION

Optical coherence tomography disclosed the structure of the vitelliform lesion in vivo and could be helpful for its pathological interpretation.

摘要

目的

报告通过光学相干断层扫描(OCT)获得的成人发病型卵黄样黄斑营养不良患者视网膜和脉络膜的横断面结构。

方法

对7例成人发病型卵黄样黄斑营养不良患者和1例Best病患者进行了眼底镜检查、荧光素和吲哚菁绿血管造影以及OCT检查。3例患者还接受了眼电图检查。

结果

  1. 7例成人发病型卵黄样黄斑营养不良患者显示出一条高反射带的边界清晰的隆起,对应于视网膜色素上皮。2. 在这7例患者中,该带下方的间隙不均匀且反射适中。3. 7例中有4例有明确的后边界。4. Best病患者在OCT上表现出不同的情况,尽管病变轮廓与其他患者相似。

结论

光学相干断层扫描在体内揭示了卵黄样病变的结构,有助于对其进行病理学解释。

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