脂质体两性霉素B在播散性球孢子菌病治疗中的应用。
Use of liposomal amphotericin B in the treatment of disseminated coccidioidomycosis.
作者信息
Antony Suresh, Dominguez Delfina C, Sotelo Elsa
机构信息
U.S. Oncology, El Paso Cancer Treatment Center, 7848 Gateway East, El Paso, TX 79915, USA.
出版信息
J Natl Med Assoc. 2003 Oct;95(10):982-5.
Abstract
Disseminated fungal infection is an important cause of morbidity and mortality, especially in immunocompromised hosts. Amphotericin B is an important part of the therapy and treatment of invasive and life-threatening mycoses. We present a case of disseminated coccidioidomycosis in a patient who was successfully treated with liposomal amphotericin B (AmBisome) on steroid therapy. It appears that liposomal amphotericin B may offer an alternative and safe option in the treatment of coccidioidomycosis when conventional amphotericin B cannot be used.
摘要
播散性真菌感染是发病和死亡的重要原因，尤其是在免疫功能低下的宿主中。两性霉素B是侵袭性和危及生命的真菌病治疗的重要组成部分。我们报告一例播散性球孢子菌病患者，该患者在接受类固醇治疗时成功接受了脂质体两性霉素B（安必素）治疗。当不能使用传统两性霉素B时，脂质体两性霉素B似乎可为球孢子菌病的治疗提供一种替代且安全的选择。
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