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术后恶心呕吐:当前文献综述

Postoperative nausea and vomiting: a review of current literature.

作者信息

Ku C M, Ong B C

机构信息

Department of Anaesthesia and Surgical Intensive, Singapore General Hospital, Outram Road, Singapore 169608.

出版信息

Singapore Med J. 2003 Jul;44(7):366-74.

Abstract

INTRODUCTION

Postoperative nausea and vomiting (PONV) is one of the commonest complaints following anaesthesia, and can result in morbidity like wound dehiscence, bleeding, pulmonary aspiration of gastric contents, fluid and electrolyte disturbances, delayed hospital discharge, unexpected hospital admission, and decreased patient satisfaction.

METHOD

A literature search was done on the Medline and relevant articles chosen.

RESULTS

Despite the vast amount of research done in this field and the variety of antiemetic drugs available, PONV still has a high incidence. Many factors are associated with PONV. Quantifying the relative impact of risk factors on PONV has resulted in the development of risk models, which can stratify risk categories and hence allow the anaesthetist to identify those patients at higher risk for PONV. The management of PONV requires a multi-modal approach which can include the use of less emetogenic anaesthetic techniques, balanced analgesia, appropriate intravenous hydration, the use of pharmacotherapy and possibly non-pharmacologic methods.

CONCLUSIONS

The use of risk models facilitates the judicious use of pharmacotherapy to ameliorate PONV especially in the high-risk patient and may lead to a more cost effective and efficient means of managing PONV.

摘要

引言

术后恶心呕吐(PONV)是麻醉后最常见的不适之一,可导致诸如伤口裂开、出血、胃内容物肺误吸、液体和电解质紊乱、住院时间延长、意外再次入院以及患者满意度下降等并发症。

方法

在Medline上进行了文献检索并选取了相关文章。

结果

尽管该领域已开展了大量研究且有多种止吐药物可供使用,但PONV的发生率仍然很高。许多因素与PONV相关。对危险因素对PONV的相对影响进行量化,从而产生了风险模型,该模型可以对风险类别进行分层,进而使麻醉医生能够识别出PONV风险较高的患者。PONV的管理需要采用多模式方法,其中可包括使用致吐性较低的麻醉技术、平衡镇痛、适当的静脉补液、药物治疗以及可能的非药物方法。

结论

风险模型的使用有助于明智地使用药物治疗来改善PONV,尤其是在高危患者中,并且可能会带来一种更具成本效益且高效的PONV管理方法。

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