使用不同反应器配置的海生糖多孢菌NUV-5固定化细胞生产新霉素的研究：技术说明
Studies on neomycin production using immobilized cells of S marinensis NUV-5 in various reactor configurations: a technical note.
作者信息
Ellaiah Poluri, Srinivasulu Bandi, Adinarayana Kunamneni
机构信息
Pharmaceutical Biotechnology Division, Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India.
出版信息
AAPS PharmSciTech. 2003;4(3):E46. doi: 10.1208/pt040346.
Abstract
Stirred tank, fluidized bed, and airlift reactors produced similar neomycin activity with immobilized cells. Packed bed reactor clearly under performed, probably because of insufficient aeration or mixing. Neomycin production using immobilized cells in fermentors requires good mixing and aeration.
摘要
搅拌罐式反应器、流化床反应器和气升式反应器在使用固定化细胞时产生的新霉素活性相似。填充床反应器的表现明显较差，可能是由于曝气或混合不足。在发酵罐中使用固定化细胞生产新霉素需要良好的混合和曝气。
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A new streptomycete producing neomycin (B&C) complex-S. marinensis (Part I).一种新的产生新霉素（B和C）复合物的链霉菌——海洋链霉菌（第一部分）。
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