Csata S, Bocskai T
Department of Urology, Municipal St. István Hospital-Outpatient Clinic, Budapest.
Ther Hung. 1992;40(2):72-5.
Forty-three patients suffering from acute or chronic urinary tract infections have been treated with pefloxacin at the Department of Urology of St. Istán Hospital. Twenty-three patients received oral doses (2 x 400 mg), 1 tabl. in the mornings and 1 in the evenings. Eighteen patients were given 2 x 1 intravenous ampoule (2 x 400 mg) dissolved in 250 ml 5% glucose in slow drip infusion. Both the oral and intravenous doses were given in the patients for 10 days. In two patients complications was observed--in one case rhagades were formed on the lip and face due to photo-sensibilization, in the other case the drug administration had to be discontinued because of nausea and vomiting. These symptoms ceased after the discontinuance of the drug. The clinical conditions, the routes of administration, clinical and bacteriological results are summarized in tables. On the basis of a low number of cases it has been concluded that pefloxacin is a new valuable antibacterial drug the use of which resulted in recovery in 15 out of 18 patients' acute and chronic infections of the urogenital system.
圣伊什特万医院泌尿外科对43例急慢性尿路感染患者使用了培氟沙星进行治疗。23例患者接受口服剂量（2×400毫克），每日1次，每次1片，早上1片，晚上1片。18例患者静脉滴注2×1支安瓿（2×400毫克），溶于250毫升5%葡萄糖溶液中缓慢滴注。口服和静脉剂量均给药10天。观察到2例患者出现并发症——1例因光致敏在嘴唇和面部形成皲裂，另1例因恶心和呕吐不得不停药。停药后这些症状消失。临床情况、给药途径、临床和细菌学结果汇总于表格中。基于病例数较少得出结论，培氟沙星是一种新的有价值的抗菌药物，18例急慢性泌尿生殖系统感染患者中有15例使用该药后康复。
