缓释安非他酮过量：过量用药后症状持续时间延长的一个重要原因。
Sustained release bupropion overdose: an important cause of prolonged symptoms after an overdose.
作者信息
Jepsen F, Matthews J, Andrews F J
机构信息
Accident and Emergency Department, Whiston Hospital, Prescot, UK.
出版信息
Emerg Med J. 2003 Nov;20(6):560-1. doi: 10.1136/emj.20.6.560.
The case is reported of a patient who had taken a deliberate overdose of sustained release bupropion. The patient suffered from prolonged symptoms including seizures before fully recovering. The prescription of bupropion is encouraged as an aid to smoking cessation and it is probable that bupropion overdose will become more common. Emergency departments need to be aware that patients taking an overdose of sustained release bupropion may have a delayed onset and prolonged course of symptoms. The pharmacology, clinical features, and treatment of bupropion overdose are discussed.
本文报告了一例故意过量服用缓释安非他酮的患者。该患者出现了包括癫痫发作在内的长时间症状，最终才完全康复。安非他酮作为戒烟辅助药物的处方被广泛使用，因此安非他酮过量服用可能会变得更加常见。急诊科需要意识到，服用过量缓释安非他酮的患者可能会出现症状延迟发作和病程延长的情况。本文还讨论了安非他酮过量服用的药理学、临床特征及治疗方法。
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