Graversen H P, Zedeler K, Andersen J A, Axelsson C K, Blichert-Toft M
Odense Sygehus, kirurgisk afdeling K.
Ugeskr Laeger. 1992 Nov 23;154(48):3392-5.
The present study evaluates the extent of axillary dissection as part of the primary surgical treatment of operable breast cancer. Data are from the period January 1979 to August 1990 and were collected prospectively as part of the Danish Breast Cancer Cooperative Group protocols for low-risk mammary carcinoma. The series consists of 6774 breast cancer patients aged 69 years or younger. The number of axillary lymph nodes removed was related to the frequency of ipsilateral axillary recurrence, recurrence-free survival, and overall survival after a median of five years follow-up, respectively. The recurrence-free survival and overall survival rate were directly related to the number of axillary lymph nodes removed. The difference in outcome is believed to be caused by false-negative classification of axillary-positive high-risk patients in groups of patients where only a few axillary lymph nodes were removed.
本研究评估了腋窝清扫范围作为可手术乳腺癌主要外科治疗一部分的情况。数据来自1979年1月至1990年8月期间，作为丹麦乳腺癌协作组低风险乳腺癌方案的一部分进行前瞻性收集。该系列包括6774例69岁及以下的乳腺癌患者。在中位随访五年后，切除的腋窝淋巴结数量分别与同侧腋窝复发频率、无复发生存率和总生存率相关。无复发生存率和总生存率与切除的腋窝淋巴结数量直接相关。据信，结果的差异是由仅切除少数腋窝淋巴结的患者组中腋窝阳性高危患者的假阴性分类导致的。
