Veĭn A M, Efremova I N, Filatova E G
Zh Nevrol Psikhiatr Im S S Korsakova. 2003;103(10):45-9.
Clinical phenomenon of migraine aura and comparison of main types of migraine were studied, using a method of visual evoked potentials (VEP) in 46 patients with migraine with aura, in 30--without aura and in 10 healthy controls. Common features as well as differences were revealed. Patients with migraine with aura were distinguished by significantly higher mean amplitudes of P300 component and by more frequents unstable VEP registration as compared to those without aura. Qualitative changes of amplitude and configuration and reduction of latent P300 period concomitant with headache side had the same frequency in both groups. In intra-group clinico-neurophysiological analysis, in regard to visual aura phenomena, the attacks with simple phenomena were the most severe in frequency, combinations with other aura symptoms, clinical and neurophysiological signs of visual system hyperexcitability.
采用视觉诱发电位(VEP)方法,对46例有先兆偏头痛患者、30例无先兆偏头痛患者及10名健康对照者进行了偏头痛先兆的临床现象及主要偏头痛类型的比较研究。揭示了其共同特征及差异。与无先兆偏头痛患者相比,有先兆偏头痛患者的P300成分平均波幅显著更高,VEP记录不稳定的情况更频繁。两组中,伴随头痛侧出现的波幅和波形的定性改变以及P300潜伏期缩短的频率相同。在组内临床神经生理学分析中,就视觉先兆现象而言,单纯现象发作的频率最高,伴有其他先兆症状、视觉系统过度兴奋的临床和神经生理学体征。