Spreafico C, Frigerio R, Santoro P, Ferrarese C, Agostoni E
Divisione di Neurologia, Ospedale Niguarda, Piazza Ospedale Maggiore 3, I-20162 Milan, Italy.
Neurol Sci. 2004 Oct;25 Suppl 3:S288-90. doi: 10.1007/s10072-004-0313-5.
Migraine is a chronic disorder. Visual symptoms and hypersensitivity to light stimuli are common. The aim of this study is the analysis of visual system in migraineurs by visual evoked potentials (VEP). We studied 53 migraineurs (21 with prophylactic migraine treatment and 32 without preventive therapy) and 20 healthy control subjects. We found lower P100 latencies in migraineurs without therapy compared to controls. In treated patients, P100 latencies showed the same trend seen in the control group. We speculate a different responsiveness of the visual system in migraineurs probably due to a dysmodulation of sensor input leading to facilitation of visual processing.
偏头痛是一种慢性疾病。视觉症状和对光刺激的超敏反应很常见。本研究的目的是通过视觉诱发电位（VEP）分析偏头痛患者的视觉系统。我们研究了53名偏头痛患者（21名接受预防性偏头痛治疗，32名未接受预防性治疗）和20名健康对照者。我们发现，未接受治疗的偏头痛患者的P100潜伏期比对照组短。在接受治疗的患者中，P100潜伏期呈现出与对照组相同的趋势。我们推测偏头痛患者视觉系统的反应性不同，可能是由于感觉输入的调节异常导致视觉处理的易化。
