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伴有通气功能障碍和呼吸功能不全的多发性肌炎

[Polymyositis with ventilatory incapacity and respiratory insufficiency].

作者信息

López Gastón Osvaldo, Malvino Eduardo, Mc Loughlin Diego, López Javier, Nitsche Alejandro, Cueva Fernando

机构信息

División Terapia Intensiva, Policlínico Bancario, Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 2003;63(5):413-6.

Abstract

The inflammatory diseases of muscle are a group of disorders characterized by proximal muscle weakness. Most cases fall into three major diagnostic categories, polymyositis (PM), dermatomyositis and inclusion body myositis. Respiratory complications are a common feature and are an important cause of morbidity and mortality. The three main types of pulmonary involvement are interstitial lung disease, aspiration pneumonia and ventilatory incapacity (VI) due to muscle weakness. There are few reported cases in which mechanical ventilation has been used in patients with PM and VI in absence of lung disease. We present a patient with PM and VI due to muscle weakness who underwent therapy maintenance with mechanical ventilator and was weaned 4 months later.

摘要

肌肉炎性疾病是一组以近端肌无力为特征的病症。大多数病例可分为三大主要诊断类别:多发性肌炎(PM)、皮肌炎和包涵体肌炎。呼吸并发症是常见特征,也是发病和死亡的重要原因。肺部受累的三种主要类型是间质性肺疾病、吸入性肺炎和因肌无力导致的通气功能不全(VI)。在没有肺部疾病的PM和VI患者中,使用机械通气的报道病例很少。我们报告一例因肌无力导致PM和VI的患者,该患者接受了机械通气维持治疗,并在4个月后脱机。

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