Zarin Jeffrey, Grosvenor David, Schurman David, Goodman Stuart
Department of Orthopaedic Surgery, Stanford University Medical Center, 300 Pasteur Drive, Room R-144, Stanford, CA 94305, USA.
J Bone Joint Surg Am. 2003 Nov;85(11):2147-51. doi: 10.2106/00004623-200311000-00013.
Patients undergoing revision total hip arthroplasty frequently require perioperative blood transfusion, increasing the risk for blood-borne disease and anaphylactic and hemolytic reactions. The purpose of this retrospective study was to evaluate the effect of intraoperative blood collection and reinfusion on net blood loss in patients undergoing revision hip arthroplasty.
The medical records of 126 patients who had had a revision total hip arthroplasty with intraoperative blood salvage, with use of a collection and reinfusion device, during a twenty-eight-month period were reviewed. For comparison, the medical records of ninety-six patients who had undergone revision hip arthroplasty without intraoperative blood salvage were reviewed. Each of the 222 patients was categorized into a group on the basis of the type of revision.
Patients who had a revision of the femoral and acetabular components (Group C) had significantly higher mean intraoperative and total blood loss than did those who had a revision of the femoral component only (Group A [p = 0.009 and p = 0.02, respectively]) or a revision of the acetabular component only (Group B [p = 0.0001 for both]). Total blood loss was not significantly different between Groups A and B. The mean amount of blood reinfused intraoperatively was 356 mL for the patients in Group A, 374 mL for the patients in Group B, and 519 mL for the patients in Group C. Regression analysis showed a significant decrease in net blood loss with intraoperative collection and reinfusion in Groups B (p = 0.002) and C (p = 0.0001) but not in Group A.
Intraoperative collection and reinfusion substantially decreased net perioperative blood loss in patients who had a revision of both components (Group C) and in those who had a revision of the acetabular component (Group B). The use of intraoperative blood collection and reinfusion appears to be a valuable method of preserving blood volume in the perioperative period.
接受翻修全髋关节置换术的患者常常需要围手术期输血,这增加了血源性疾病以及过敏和溶血反应的风险。这项回顾性研究的目的是评估术中血液回收与回输对接受翻修髋关节置换术患者净失血量的影响。
回顾了28个月期间126例行翻修全髋关节置换术且术中使用血液回收与回输装置进行自体血回收的患者的病历。为作比较,还回顾了96例未进行术中血液回收的翻修髋关节置换术患者的病历。根据翻修类型将这222例患者中的每一例归入相应组。
同时翻修股骨和髋臼部件的患者(C组)术中及总失血量的均值显著高于仅翻修股骨部件的患者(A组,分别为p = 0.009和p = 0.02)或仅翻修髋臼部件的患者(B组,两者均为p = 0.0001)。A组和B组之间的总失血量无显著差异。A组患者术中回输的平均血量为356 mL,B组为374 mL,C组为519 mL。回归分析显示,B组(p = 0.002)和C组(p = 0.0001)通过术中血液回收与回输使净失血量显著减少,而A组未减少。
术中血液回收与回输可显著减少同时翻修两个部件的患者(C组)以及翻修髋臼部件的患者(B组)围手术期的净失血量。术中血液回收与回输似乎是围手术期保存血容量的一种有效方法。