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髋关节置换术中术中细胞回收与术后自体输血:一项回顾性服务评估

Intraoperative cell salvage versus postoperative autologous blood transfusion in hip arthroplasty: a retrospective service evaluation.

作者信息

Mason L, Fitzgerald C, Powell-Tuck J, Rice R

机构信息

Trauma and Orthopaedic Department, Nevill Hall Hospital, Abergavenny, UK.

出版信息

Ann R Coll Surg Engl. 2011 Jul;93(5):398-400. doi: 10.1308/003588411X579801.

Abstract

INTRODUCTION

A number of ways of reducing blood loss in arthroplasty have been explored, including preoperative autologous transfusion, intraoperative cell salvage and postoperative autologous transfusions. Both intraoperative blood salvage and postoperative retransfusion drains have been shown to be effective in reducing blood loss in total hip arthroplasty. In our department there was a change in practice from using postoperative retransfusion drains to intraoperative cell salvage. To our knowledge no study has directly compared using intraoperative blood salvage and postoperative retransfusion drains alone in total hip arthroplasty.

METHODS

This was a retrospective service evaluation including all primary hip arthroplasty performed under our care between January 2006 and December 2008. Patients were divided into two groups: Group A used a postoperative autologous blood transfusion (ABT) drain and Group B used intraoperative cell salvage.

RESULTS

A total of 144 patients were included in this study: 84 in Group A and 60 in Group B. The mean haemoglobin difference for Group A was 3.96g/dl (standard deviation [SD]: 1.52) and for Group B it was 3.46g/dl (SD: 1.42). The mean haematocrit difference for Group A was 0.12% (SD: 0.05) and for Group B it was 0.10% (SD: 0.04). Using an independent t-test for the comparison of means, a significant difference was found between Group A and B both in regards to haemoglobin difference (p=0.009) and haematocrit difference (p=0.046).

CONCLUSIONS

We feel that intraoperative cell salvage provides a more efficient method of reducing blood loss than postoperative retransfusion in primary total hip replacement. A prospective randomised study would be useful to ascertain any clinical difference between the two methods.

摘要

引言

人们已经探索了多种减少关节置换术中失血的方法,包括术前自体输血、术中血液回收和术后自体输血。术中血液回收和术后回输引流均已被证明在减少全髋关节置换术中的失血方面是有效的。在我们科室,实践中已从使用术后回输引流改为术中血液回收。据我们所知,尚无研究直接比较全髋关节置换术中单独使用术中血液回收和术后回输引流的情况。

方法

这是一项回顾性服务评估,纳入了2006年1月至2008年12月在我们照护下进行的所有初次髋关节置换术。患者分为两组:A组使用术后自体输血(ABT)引流,B组使用术中血液回收。

结果

本研究共纳入144例患者:A组84例,B组60例。A组的平均血红蛋白差异为3.96g/dl(标准差[SD]:1.52),B组为3.46g/dl(SD:1.42)。A组的平均血细胞比容差异为0.12%(SD:0.05),B组为0.10%(SD:0.04)。使用独立t检验比较均值,发现A组和B组在血红蛋白差异(p = 0.009)和血细胞比容差异(p = 0.046)方面均存在显著差异。

结论

我们认为,在初次全髋关节置换术中,术中血液回收比术后回输提供了一种更有效的减少失血的方法。一项前瞻性随机研究将有助于确定这两种方法之间的任何临床差异。

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