Cerizzi A, Crosta C, Botti F, Carrara A, Alloni R, Taschieri A M
Istituto di Chirurgia generale e toracica, Università degli Studi di Milano.
Ann Ital Chir. 1992 Jul-Aug;63(4):465-9; discussion 469-70.
Accurate staging of gastric malignancy can only be obtained at surgery and after detailed histological examination of the resection specimen. Endoscopic ultrasonography may provide accurate detection and staging of gastric cancer because of its ability to visualize both the intramural and extramural extent of the lesion and any adjacent lymph node involvement. From february 90 to april 91, 29 patients with a gastric carcinoma were studied endosonographically before surgery. All studies were performed with an Olympus EU-M3. Preoperative TNM classification and a prediction of the resectability of gastric cancer were done in every patient. The results were matched with those obtained with the histology of resected specimens according to the TNM classification 1987. Endoscopic ultrasonography was accurate in assessing the extent and depth of tumor infiltration. The overall accuracy rate was 90.5% (19 out of 21 patients). Overstaging occurred in 9.5% of the cases (2 patients); none understaging occurred. EUS was less accurate in assessment of lymph node metastasis; the overall accuracy rate was 57.1%. Distinction between reactive lymph node and small micrometastatic lymph node involvement could be hard. Local resectability was correctly diagnosed with EUS in each of 23 patients; in two patients an intramural mass with a deep infiltration into the surrounding tissue was correctly diagnosed. In our opinion EUS is an essential diagnostic procedure in the clinical staging of the gastric cancer.
胃恶性肿瘤的准确分期只能在手术时以及对切除标本进行详细组织学检查后才能获得。内镜超声检查能够显示病变的壁内和壁外范围以及任何相邻淋巴结受累情况,因此可提供胃癌的准确检测和分期。从1990年2月至1991年4月,对29例胃癌患者在手术前进行了内镜超声检查。所有检查均使用奥林巴斯EU-M3进行。对每位患者进行了术前TNM分类和胃癌可切除性的预测。结果与根据1987年TNM分类法从切除标本的组织学检查中获得的结果进行了匹配。内镜超声检查在评估肿瘤浸润的范围和深度方面是准确的。总体准确率为90.5%(21例患者中有19例)。9.5%的病例(2例患者)出现分期过高的情况;未出现分期过低的情况。内镜超声在评估淋巴结转移方面准确性较低;总体准确率为57.1%。区分反应性淋巴结和微小转移性淋巴结受累可能比较困难。23例患者中,每例患者的局部可切除性均通过内镜超声正确诊断;2例患者中,壁内肿块并伴有向周围组织的深度浸润被正确诊断。我们认为内镜超声是胃癌临床分期中必不可少的诊断程序。