Takashi Munehisa, Matsuyama Mutsushi, Furuhashi Kenichi, Kodama Yukihiro, Shinzato Masanori, Shamoto Mikihiro, Nakashima Nobuo
Department of Urology, Hekinan Municipal Hospital, Hekinan, Aichi, Japan.
Int J Urol. 2003 Nov;10(11):603-6. doi: 10.1046/j.1442-2042.2003.00698.x.
Approximately 30 cases of carcinoid tumor of the kidney have been reported in the English literature, including three cases found as components of teratomas. Renal composite tumors associated with somatostatinoma have not been described. A 53-year-old female presented with an incidentally found right renal cystic lesion. Computed tomography demonstrated a cystic lesion associated with a solid nodule in the right kidney and postcontrast dynamic MRI revealed enhancement of the solid nodule. The patient underwent radical nephrectomy for the kidney lesion and is now well without recurrence 21 months after the operation. From the histopathological findings we diagnosed the cystic lesion as a composite tumor composed of mucinous cystadenoma and carcinoid tumor. Immunohistochemistry demonstrated the majority of cells of in carcinoid portion to be positive for antisomatostatin staining. The present case is the first documented composite tumor of mucinous cystadenoma and somatostatinoma of the kidney.
英文文献中已报道了约30例肾类癌肿瘤，其中3例是畸胎瘤的组成部分。尚未有与生长抑素瘤相关的肾复合肿瘤的描述。一名53岁女性偶然发现右肾囊性病变。计算机断层扫描显示右肾有一个与实性结节相关的囊性病变，增强后动态磁共振成像显示实性结节有强化。患者因肾病变接受了根治性肾切除术，术后21个月情况良好，无复发。根据组织病理学检查结果，我们将囊性病变诊断为黏液性囊腺瘤和类癌肿瘤组成的复合肿瘤。免疫组织化学显示类癌部分的大多数细胞抗生长抑素染色呈阳性。本病例是首例有记录的肾黏液性囊腺瘤和生长抑素瘤复合肿瘤。
