Cusi D, Taglietti M V, Liccardo A
Cattedra e Scuola di Specializzazione in Nefrologia, Universita' degli Studi di Milano, Italy.
G Ital Nefrol. 2003 Sep-Oct;20(5):516-24.
We illustrate two cases of pregnancy complicated by previously onset chronic nephropathy. In spite of two completely different pathogenetic mechanisms for chronic renal insufficiency (IgA nephropathy in one case and vescico-ureteral reflux in the other), renal function at the beginning of the pregnancy was similar and only partially impaired. In either case the pregnancy lowered by 50% the residual glomerular filtration rate. Only minimum recovery was observed during several months of follow-up.
我们阐述了两例妊娠合并既往已发病的慢性肾病的病例。尽管慢性肾功能不全存在两种完全不同的发病机制（一例为IgA肾病，另一例为膀胱输尿管反流），但妊娠开始时的肾功能相似且仅部分受损。在这两种情况下，妊娠均使残余肾小球滤过率降低了50%。在数月的随访期间仅观察到最小程度的恢复。
