Asakawa Deanna S, Nayak Krishna S, Blemker Silvia S, Delp Scott L, Pauly John M, Nishimura Dwight G, Gold Garry E
Department of Mechanical Engineering, Stanford University, Stanford, California 94305, USA.
J Magn Reson Imaging. 2003 Dec;18(6):734-9. doi: 10.1002/jmri.10422.
To test the feasibility of using real-time phase contrast (PC) magnetic resonance imaging (MRI) to track velocities (1-20 cm/second) of skeletal muscle motion.
To do this we modified a fast real-time spiral PC pulse sequence to accommodate through-plane velocity encoding in the range of -20 to +20 cm/second. We successfully imaged motion of the biceps brachii and triceps brachii muscles during elbow flexion and extension in seven unimpaired adult subjects using real-time PC MRI.
The velocity data demonstrate that the biceps brachii and the triceps brachii, antagonistic muscles, move in opposite directions during elbow flexion and extension with velocity values in the muscle tissue ranging from -10 to +10 cm/second.
With further development, real-time PC MRI may provide a means to analyze muscle function in individuals with neurologic or movement disorders who cannot actively complete the repeated motions required for dynamic MRI techniques, such as cine PC MRI, that are more commonly used in musculoskeletal biomechanics applications.
测试使用实时相位对比（PC）磁共振成像（MRI）追踪骨骼肌运动速度（1 - 20厘米/秒）的可行性。
为此，我们修改了快速实时螺旋PC脉冲序列，以适应-20至+20厘米/秒范围内的层面内速度编码。我们使用实时PC MRI成功地对7名未受损成年受试者在肘关节屈伸过程中肱二头肌和肱三头肌的运动进行了成像。
速度数据表明，拮抗肌肱二头肌和肱三头肌在肘关节屈伸过程中向相反方向运动，肌肉组织中的速度值范围为-10至+10厘米/秒。
随着进一步发展，实时PC MRI可能为分析患有神经或运动障碍的个体的肌肉功能提供一种方法，这些个体无法主动完成动态MRI技术（如电影PC MRI，更常用于肌肉骨骼生物力学应用）所需的重复运动。
