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对伴有支架内闭塞性再狭窄的陈旧性退化隐静脉移植物进行β射线近距离治疗。

Beta brachytherapy of an old degenerated saphenous vein graft with occlusive in-stent restenosis.

作者信息

Ortolani Paolo, Marzocchi Antonio, Gaiba William, Neri Stefano, Marrozzini Cinzia, Palmerini Tullio, Aquilina Matteo, Branzi Angelo

机构信息

Institute of Cardiology, University of Bologna, Bologna, Italy.

出版信息

Ital Heart J. 2003 Sep;4(9):646-50.

PMID:14635385
Abstract

We report a case of obstructive in-stent restenosis in a diffusely diseased saphenous vein graft complicated by a non-ST-elevation myocardial infarction. With tirofiban infusion, the extensively occluded saphenous bypass was reperfused, establishing a TIMI flow 3, and then entirely irradiated with a beta source (32P) without any complication. At 7 months the patient was asymptomatic and the control angiogram did not reveal any restenosis. In conclusion, 32P beta brachytherapy may be extremely effective not only in case of native vessel in-stent restenosis but also in cases of high-risk vein graft in-stent restenosis.

摘要

我们报告了1例大隐静脉移植血管弥漫性病变并发非ST段抬高型心肌梗死的支架内阻塞性再狭窄病例。通过输注替罗非班,广泛闭塞的大隐静脉搭桥血管实现了再灌注,血流达到TIMI 3级,随后用β射线源(32P)进行了全程照射,未出现任何并发症。7个月时患者无症状,对照血管造影未显示任何再狭窄。总之,32Pβ近距离放射治疗不仅对自体血管支架内再狭窄有效,对高危静脉移植血管支架内再狭窄也可能极为有效。

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