Noda Yoshihiro, Sonoda Koh Hei, Nakamura Takehiko, Kawano Yoh Ichi, Ishibashi Tatsuro, Inomata Hajime
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Jpn J Ophthalmol. 2003 Nov-Dec;47(6):591-4. doi: 10.1016/s0021-5155(03)00146-1.
Vogt-Koyanagi-Harada (VKH) disease patients with the complication of subretinal pigmented proliferative tissue tend to have a poor visual prognosis.
We herein report a case of VKH with good visual acuity despite a prominent subretinal fold.
A 24-year-old woman, who experienced several recurrent episodes of VKH disease, had bilateral serous retinal detachment with poor vision (RE 20/40 and LE 20/25). After the administration of high doses of systemic corticosteroids and D-mannitol, the subretinal fluid disappeared and the sensory retinas gradually became reattached. During the course of therapy, prominent pigmented subretinal strands were formed in both eyes. Optical coherence tomography disclosed that the strands existed at the retinal pigment epithelium level. Amazingly, we observed a change in the location of the fold in the posterior retina during the course of the disease. The patient finally showed the "sunset glow" fundi and a subretinal fold that was located almost directly beneath both fovea. Fortunately, this patient was able to recover and finally achieve a good visual acuity (RE 20/17 and LE 20/17).
We reported a VKH disease patient with a good visual acuity despite a remarkable subfoveal fold, which changed its location during the course of the disease.
患有视网膜下色素增生性组织并发症的Vogt-小柳-原田(VKH)病患者往往视力预后较差。
我们在此报告一例VKH病患者,尽管存在明显的视网膜下褶皱,但视力良好。
一名24岁女性,经历了几次VKH病复发,双眼发生浆液性视网膜脱离,视力较差(右眼20/40,左眼20/25)。在给予高剂量全身皮质类固醇和D-甘露醇后,视网膜下液消失,感觉视网膜逐渐复位。在治疗过程中,双眼均形成了明显的色素性视网膜下条索。光学相干断层扫描显示条索存在于视网膜色素上皮层。令人惊讶的是,我们在疾病过程中观察到后极部视网膜褶皱位置发生了变化。患者最终出现了“晚霞样”眼底,且视网膜下褶皱几乎直接位于两个黄斑中心凹下方。幸运的是,该患者得以康复,最终视力良好(右眼20/17,左眼20/17)。
我们报告了一例VKH病患者,尽管黄斑中心凹下有明显褶皱且在疾病过程中其位置发生了变化,但视力良好。