Suppr超能文献

硬膜下导管移位可能导致巴氯芬泵功能障碍。

Subdural catheter migration may lead to baclofen pump dysfunction.

作者信息

Pasquier Y, Cahana A, Schnider A

机构信息

Spinal Cord Unit, Clinic of Reeducation, Department of Clinical Neuroscience, University Hospital of Geneva, Switzerland.

出版信息

Spinal Cord. 2003 Dec;41(12):700-2. doi: 10.1038/sj.sc.3101536.

Abstract

OBJECTIVES

To report an unusual cause of intrathecal drug delivery failure in baclofen pump device.

STUDY DESIGN

A case report of an SCI patient treated with intrathecal baclofen, presenting a drug withdrawal.

SETTING

Regional spinal cord injuries centre in Geneva (Switzerland).

METHODS

We present a case of a 38-year-old male with complete T9 spastic paraplegia for 15 years, treated with intrathecal baclofen for 11 years. He recently presented to our centre with a spastic hypertonic episode, associated with rhabdomyolysis.

RESULTS

Standard investigations were unrevealing. However, a CT scan performed after injecting a radio-opaque solution by the side port of the pump, showed an unexpected catheter migration into the subdural space. Surgical revision reversed withdrawal symptoms.

CONCLUSIONS

Subdural catheter migration must be considered in the differential diagnosis of intrathecal drug delivery system failures. We recommend the use of the CT scan after contrast injection, to detect the localization of the distal catheter tip and confirm the normal diffusion into the subarachnoid space.

摘要

目的

报告巴氯芬泵装置鞘内给药失败的一种罕见原因。

研究设计

一名接受鞘内巴氯芬治疗的脊髓损伤(SCI)患者出现药物戒断的病例报告。

地点

瑞士日内瓦的地区脊髓损伤中心。

方法

我们报告一例38岁男性,T9完全性痉挛性截瘫15年,接受鞘内巴氯芬治疗11年。他最近因痉挛性高张力发作并伴有横纹肌溶解症前来我们中心就诊。

结果

标准检查未发现异常。然而,通过泵的侧端口注入不透射线溶液后进行的CT扫描显示,导管意外迁移至硬膜下间隙。手术修复逆转了戒断症状。

结论

硬膜下导管迁移必须纳入鞘内给药系统故障的鉴别诊断中。我们建议在注入造影剂后进行CT扫描,以检测导管远端尖端的位置并确认造影剂正常扩散至蛛网膜下腔。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验