Nitta E, Iwasa Y, Sugita M, Hirono C, Shiba Y
Department of Oral Physiology, Hiroshima University Graduate School of Biomedical Sciences, Minami-ku, Hiroshima, Japan.
J Oral Rehabil. 2003 Dec;30(12):1209-15. doi: 10.1111/j.1365-2842.2003.01196.x.
Mastication and swallowing increase the heart rate, and posture change and respiration also modulate the heart rate. To clarify the role of mastication and swallowing in the modulation of the autonomic nervous activity, we investigated how they interact with modulation of the heart rate by changing body positions and respiration in young healthy subjects. R-R intervals of electrocardiogram at rest were significantly changed with different body positions, compared with supine and standing. A net shortening by mastication of a chewing gum base was similar in various postures. Respiration induced a periodic change in the R-R intervals, depending on the body postures, but mastication did not markedly change them in each posture. Dry swallowing at rest and spontaneous swallowing during the mastication in the sitting position induced a similar transient shortening and suppressed the respiration-induced changes after the swallowing. The net transient shortening by dry swallowing at rest was similar in the different postures. These results suggest that signals from mastication and swallowing are summated with those from body positions and respiration for shortening the R-R intervals and that signals from swallowing suppress the respiration-induced periodic changes.
咀嚼和吞咽会增加心率，体位变化和呼吸也会调节心率。为了阐明咀嚼和吞咽在自主神经活动调节中的作用，我们研究了在年轻健康受试者中，它们如何通过改变体位和呼吸与心率调节相互作用。与仰卧位和站立位相比，静息时心电图的R-R间期会因不同体位而发生显著变化。咀嚼口香糖基料时，其净缩短在各种体位下相似。呼吸会引起R-R间期的周期性变化，这取决于体位，但咀嚼在每种体位下并不会显著改变它们。静息时的干吞咽以及坐位咀嚼时的自发吞咽会引起类似的短暂缩短，并抑制吞咽后呼吸引起的变化。静息时干吞咽的净短暂缩短在不同体位下相似。这些结果表明，来自咀嚼和吞咽的信号与来自体位和呼吸的信号相加，以缩短R-R间期，并且来自吞咽的信号会抑制呼吸引起的周期性变化。
