Ward S L, Keens T G
Department of Pediatrics, University of Southern California School of Medicine, Los Angeles.
Clin Perinatol. 1992 Dec;19(4):849-60.
It has been reported that ISAM have an increased risk of SIDS and abnormalities of cardiorespiratory physiology. Abnormalities of cardiorespiratory control may account for the increased SIDS risk in some ISAM, and home monitoring is often used for ISAM with clinical apneic episodes. However, it is possible that the increased SIDS risk factors concentrated in this population. The increased SIDS risk SIDS risk factors concentrated in this population. The increased SIDS risk demonstrated in ISAM does not necessarily indicate that drug exposure during gestation in itself causes SIDS. Thus home monitoring is not indicated for ISAM who do not have apnea or other clinical evidence of a respiratory control abnormality.
据报道,宫内酒精综合征患儿发生婴儿猝死综合征(SIDS)的风险增加,且存在心肺生理异常。心肺控制异常可能是部分宫内酒精综合征患儿SIDS风险增加的原因,对于有临床呼吸暂停发作的宫内酒精综合征患儿,常采用家庭监测。然而,SIDS风险增加因素可能集中在这一人群中。宫内酒精综合征患儿中显示出的SIDS风险增加并不一定表明孕期药物暴露本身会导致SIDS。因此,对于没有呼吸暂停或其他呼吸控制异常临床证据的宫内酒精综合征患儿,不建议进行家庭监测。